尿酸与神经系统疾病的相关研究

君兰 何, 惠然 张, 良玉 唐, 铁标 郭

摘要


尿酸（UA）是腺嘌呤和鸟嘌呤代谢的最终氧化产物。人体尿酸 1/3 由外源性食物获取，2/3 由内源性细胞凋亡、死亡形成。近年来越来越多的研究发现，血清尿酸除会导致痛风发作、肾结石外，还与帕金森、痴呆、急性卒中等神经退行性疾病及脑血管疾病的发生相关。论文就血清尿酸与神经系统疾病相关性研究的进行如下综述，以期为相关疾病的预防及诊疗提供新的策略。

关键词


尿酸；帕金森；痴呆；卒中

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参考


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DOI: https://doi.org/10.12346/pmr.v5i1.8147

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