成人脓毒症患者预后评估相关研究进展

超 程, 立伟 滑

摘要


脓毒症具有高发病率、高致死率以及远期生活质量下降等特点,早期诊断、准确判断病情及合理评估预后,有助于临床医生及时调整干预措施,降低病死率。目前用于脓毒症患者早期病情严重程度及预后评估的方法很多,包括各类评分系统工具及感染相关生物标志物,也是当前研究的热点之一,现就常用方法及相关进展做一综述,以供临床医师参考。

关键词


脓毒症;预后;生物标志物

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参考


Angus DC, van der Poll T. Severe sepsis and septic shock[J]. N Engl J Med,2013,369(9):840-851.

Lever A, Mackenzie I. Sepsis: definition, epidemiology, and diagnosis[J]. BMJ,2007,335(7625):879-883.

Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000[J]. N Engl J Med,2003,348(16):1546-1554.

Dombrovskiy VY, Martin AA, Sunderram J, et al. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003[J]. Crit Care Med,2007,35(5):1244-1250.

Levy MM, Dellinger RP, Townsend SR, et al. The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis[J]. Intensive Care Med,2010,36(2):222-231.

江伟,杜斌.中国脓毒症流行病学现状[J].医学研究生学 报,2019,32(1):5-8.

Zhou J, Qian C, Zhao M, et al. Epidemiology and outcome of severe sepsis and septic shock in intensive care units in mainland China[J]. PLoS One,2014,9(9):e107181.

Vincent JL, Sakr Y, Sprung CL, et al. Sepsis in European intensive care units: results of the SOAP study[J]. Crit Care Med,2006,34(2):344-353.

Weng L, Zeng XY, Yin P, et al. Sepsis-related mortality in China: a descriptive analysis[J]. Intensive Care Med,2018,44(7):1071-1080.

Wang HE, Szychowski JM, Griffin R, et al. Long-term mortality after community-acquired sepsis: a longitudinal population-based cohort study[J]. BMJ Open,2014,4(1):e004283.




DOI: https://doi.org/10.12346/pmr.v4i3.6669

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