生物标志物对肠源性脓毒症病情预测的研究进展

大海 肖, 青青 王, 健 于

摘要


肠源性脓毒症是脓毒症的重要组成部分，其发病率及死亡率居高不下，给人们造成严重的经济负担，同时也降低人们的生活质量。目前对于肠源性脓毒症的诊断缺乏普遍接受的临床标准，只是将肠道感染作为脓毒症的一种重要来源，由此对于肠源性脓毒症的早期预警缺乏认识。理想的生物标志物在这方面有着超过其本身价值的作用。α 抑制蛋白、CD64、Presepsin、肝素结合蛋白、DLL1 等新型标志物被证明与脓毒症病情关系密切，对于肠源性脓毒症患者病情的早期预测十分重要，对于指导其治疗发挥着重要的价值。

关键词


肠源性脓毒症；病情预测；生物标志物；间 α 抑制蛋白；CD64

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参考


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DOI: https://doi.org/10.12346/pmr.v4i3.6668

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