炎症性肠病与传统代谢因素及代谢性药物的联系及展望

禄 郑, 毅杰 顾, 婷婷 夏

摘要


近年来有研究表明,代谢性药物如调脂药物,降压药物以及降糖药物对炎症性肠病有潜在的预防及治疗作用。论文阐述了炎症性肠病与传统代谢因素之间的相互作用,并探讨了不同类别的调脂药,降压药以及降糖药潜在的对相关人群罹患炎症性肠病的预防作用以及对炎症性肠病患者的治疗作用。

关键词


炎症性肠病;血压;血脂;血糖

全文:

PDF

参考


Park K T, Ehrlich O G, Allen J I, et al. The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn’s & Colitis Foundation[J]. Inflammatory Bowel Diseases, 2019,26(42).

Chouliaras G, Panayotou I, Margoni D, et al. Circulating leptin and adiponectin and their relation to glucose metabolism in children with Crohn's disease and ulcerative colitis[J]. Pediatric Research, 2013,74(4):420-426.

Wang C Y, Liu P Y, Liao J K.Pleiotropic effects of statin therapy: molecular mechanisms and clinical results[J].Trends in Molecular Medicine, 2008,14(1):37-44.

Grip O, Janciauskiene S, Bredberg A. Use of atorvastatin as an anti-inflammatory treatment in Crohn's disease[J]. British Journal of Pharmacology, 2010,155(7):1085-1092.

Marinelli C. et al. Serum Levels of PCSK9 Are Increased in Patients With Active Ulcerative Colitis Representing a Potential Biomarker of Disease Activity: A Cross-sectional Study[J]. J Clin Gastroenterol 2022,5(6):787-793.

Tseng C H. Metformin Use Is Associated with a Lower Risk of Inflammatory Bowel Disease in Patients with Type 2 Diabetes Mellitus[J]. J Crohns Colitis, 2021(15): 64-73.




DOI: https://doi.org/10.12346/pmr.v5i5.9138

Refbacks

  • 当前没有refback。