原发性房角关闭疾病与正常眼黄斑中心凹下脉络膜厚度对比的meta 分析

芷妍 罗, 勇 丁, 嘉琪 卢

摘要


多项研究通过光相干断层扫描(OCT)技术检测到原发性房角关闭疾病(primary angle-closure disease，PACD)与 正常眼之间脉络膜厚度(choroid thickness，CT)的差别，提示脉络膜增厚参与了 PACD 疾病的发生发展。本研究通过荟萃分 析来评估 PACD 与正常眼黄斑中心下脉络膜厚度(sub-foveal choroid thickness，SFCT)的对比，共纳入了 9 项研究，包括 784 只 PACD 眼和 495 只正常眼。荟萃分析结果表明，PACD 和正常眼的 SFCT 对比有显著差异 [SMD = 0.611(95% CI:0.493~0.730)， P=0.000]，提示黄斑中心凹下脉络膜增厚可能是 PACD 疾病发生发展的重要因素。

关键词


原发性房角关闭疾病;黄斑中心凹下脉络膜厚度;光相干断层扫描

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参考


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DOI: https://doi.org/10.12346/pmr.v5i4.8991

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