甲基乙二醛与糖尿病视网膜病变相关性分析

肖肖 董, 春蕊 任, 建凤 刘, 臣廷 王

摘要


目的：探讨甲基乙二醛（MG）检测在糖尿病视网膜病变（DR）中的诊断价值。方法：选取 2018 年 12 月至 2019年 12 月于沧州市人民医院内分泌科住院治疗的 T2DM 患者 66 例，同期健康体检中心正常人群 26 例，分为正常对照组（NC, n ＝ 26）、单纯 T2DM 组（DM, n ＝ 43）及合并 DR 组（DN, n ＝ 23），比较三组一般资料及生化指标。结果：NC 组、DM 组、DR 组血清 MG 水平呈逐渐升高趋势（P ＜ 0.05）。Pearson 相关分析显示，DR 与血清 MG 水平呈正相关（P ＜ 0.05）。二元Logistic 回归分析显示，MG 水平是 DR 的危险因素。结论：血清 MG 水平与 DR 严重程度相关，是 DR 发生的独立影响因素。

关键词


2 型糖尿病；糖尿病视网膜病变；甲基乙二醛

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参考


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DOI: https://doi.org/10.12346/pmr.v5i3.8524

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