sST2 在心力衰竭中的研究概述

兴荣 李, 贤胜 黄, 海超 高, 青雷 王, 晓晓 王

摘要


可溶性生长刺激表达基因 2 蛋白（Soluble Suppression of Tumorigenicity-2，sST2）是一种与心力衰竭相关的新生物标记物，因其表达能力不受年岁、性别、肾功等条件限制而成了一个热题。

关键词


可溶性生长刺激表达基因 2 蛋白；心力衰竭；研究

全文:

PDF

参考


Iwahana H, Yanagisawa K, Ito-Kosaka A, et al. Different promoter usage and multiple transcription initiation sites of the interleukin-1 receptor-related human ST2 gene in UT-7 and TM12 cells[J].Febs Journal, 2010,264(2):397-406.

Sanada S, Hakuno D, Higgins L J, et al. IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system[J]. Journal of Clinical Investigation, 2007,117(6):1538-1549.

Pascual-Figal DA, Januzzi JL. The biology of ST2: the International ST2 Consensus Panel[J]. Am J Cardiol, 2015 Apr 2;115(7 Suppl):3B-7B.

武希梅.可溶性ST2在急性心力衰竭患者中的诊断及预后评估价值[D].呼和浩特:内蒙古医科大学,2019.

衡奇霞,肖莉丽.血清sST2、sLOX-1检测在AHF诊断及预后中的评估价值[J].实验与检验医学,2021,39(2):302-304+312.

Dieplinger B, Gegenhuber A, Haltmayer M, et al. Evaluation of novel biomarkers for the diagnosis of acute destabilised heart failure in patients with shortness of breath[J].Heart, 2009 Sep;95(18):1508-1513.

Llibre C, Zamora E, Caballero À, et al. The real-life value of ST2 monitoring during heart failure decompensation: impact on long-term readmission and mortality[J]. Biomarkers, 2016,21(3): 225-232.

Jin Y, Wei S, Yao L. Diagnostic performance of miR-214, BNP, NT-proBNP and soluble ST2 in acute heart failure[J]. Int J Clin Pract, 2021 Oct;75(10):e14643.

杨阳,罗义.心力衰竭患者B型利钠肽、B型氨基端利钠肽原和可 溶性ST2水平变化及意义[J].广东医学,2013,34(13):2022-2025.

Mueller T, Leitner I, Egger M, et al. Association of the biomarkers soluble ST2, galectin-3 and growth-differentiation factor-15 with heart failure and other non-cardiac diseases[J]. Clin Chim Acta, 2015 May 20;445:155-60.

Emdin M, Aimo A, Vergaro G, et al. sST2 Predicts Outcome in Chronic Heart Failure Beyond NT-proBNP and High-Sensitivity Troponin T[J].J Am Coll Cardiol, 2018 Nov 6;72(19):2309-2320.

Gaggin HK, Szymonifka J, Bhardwaj A, et al. Head-to-head comparison of serial soluble ST2, growth differentiation factor-15, and highly-sensitive troponin T measurements in patients with chronic heart failure[J]. JACC Heart Fail, 2014 Feb;2(1):65-72.

Espriella R, Bayés-Genis A, Revuelta-LóPEZ E, et al.IMPROVE- HF Investigators. Soluble ST2 and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction[J].J Card Fail, 2021 Apr;27(4):427-434.

O’Meara E, Prescott MF, Claggett B, et al. Independent Prognostic Value of Serum Soluble ST2 Measurements in Patients With Heart Failure and a Reduced Ejection Fraction in the PARADIGM-HF Trial (Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure)[J]. Circ Heart Fail,2018 May;11(5):e004446.

JANUZZI J, PASCUAL F D, DANIELS L.,ST2 testing for chronic heart failure therapy monitoring: the International ST2 Consensus Panel[J].Am J Cardiol, 2015,115(7):70B-75B.




DOI: https://doi.org/10.12346/pmr.v4i6.7938

Refbacks

  • 当前没有refback。