早期生物学标志物在急性肾损伤中的研究进展

倩依 刘, 颖 郅, 清龙 卢

摘要


在医院和社区中，急性肾损伤（AKI）是一种常见且日益频繁的疾病，其可直接导致终末期肾病（ESRD），并增加患慢性肾脏疾病（CKD）和基础 CKD 恶化的风险，且 AKI 可导致不良事件、产生高成本。早期预测 AKI 并及时干预成为改善患者预后的关键。目前缺乏特异性诊断方式，临床上常用血清肌酐（Scr）和尿量来对 AKI 进行诊断和分级，但两者存在滞后性。近年来，早期检测 AKI 的一个主要进展是实施新的可靠生物学标记物，论文对临床上几种研究较热门的生物学标志物进行综述。

关键词


急性肾损伤；生物学标记物；联合检测；综述

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参考


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DOI: https://doi.org/10.12346/pmr.v4i3.6705

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