甲状旁腺切除术对血液透析患者血管功能的影响

祯 刘, 书同 杜

摘要


终末期肾脏病（ESRD）长期维持性血液透析患者继发性甲状旁腺功能亢进（SHPT）为常见的临床症状，可能导致转移性钙化的发生。多项研究结果显示可通过手术切除甲状旁腺有效降低患者血清中钙磷浓度、PTH 等从而达到延缓或改善血管钙化进展的目的。

关键词


慢性肾脏病；血液透析；PTX 术；血管钙化

全文:

PDF

参考


Shantouf R, Kovesdy C P, Kim Y, et al. Association of serum alkaline phosphatase with coronary artery calcification in maintenance hemodialysis patients[J]. Clin J Am Soc Nephrol, 2009,4(6):1106-1114.

Shanahan C M, Crouthamel M H, Kapustin A, et al. Arterial calcification in chronic kidney disease: key roles for calcium and phosphate[J]. Circ Res, 2011,109(6):697-711.

Block G A, Klassen P S, Lazarus J M, et al. Mineral metabolism, mortality, and morbidity in maintenance hemodialysis[J]. J Am Soc Nephrol, 2004,15(8):2208-2218.

Kalantar-Zadeh K, Kuwae N, Regidor D L, et al. Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients[J]. Kidney Int, 2006,70(4): 771-780.

Mermel L A, Allon M, Bouza E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America[J]. Clin Infect Dis, 2009,49(1):1-45.

Hajjej Z, Nasri M, Sellami W, et al. Incidence, risk factors and microbiology of central vascular catheter-related bloodstream infection in an intensive care unit[J]. J Infect Chemother, 2014,20(3):163-168.

Cozzolino M, Mazzaferro S, Pugliese F, et al. Vascular calcification and uremia: what do we know?[J]. Am J Nephrol, 2008,28(2):339-346.

Disthabanchong S. Vascular calcification in chronic kidney disease: Pathogenesis and clinical implication[J]. World J Nephrol, 2012,1(2):43-53.

Turkmen K, Ozcicek F, Ozcicek A, et al. The relationship between neutrophil-to-lymphocyte ratio and vascular calcification in end-stage renal disease patients[J]. Hemodial Int, 2014,18(1):47-53. [10] Bonet J, Bayes B, Fernandez-Crespo P, et al. Cinacalcet may reduce arterial stiffness in patients with chronic renal disease and secondary hyperparathyroidism - results of a small-scale, prospective, observational study[J]. Clin Nephrol, 2011,75(3):181-187.

Shih C J, Tarng D C, Yang W C, et al. Parathyroidectomy reduces intradialytic hypotension in hemodialysis patients with secondary hyperparathyroidism[J]. Kidney Blood Press Res, 2013,37(4-5):323-331.

KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)[J]. Kidney Int Suppl (2011), 2017,7(1):1-59.

Burton J O, Goldsmith D J, Ruddock N, et al. Renal association commentary on the KDIGO (2017) clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of CKD-MBD[J]. BMC Nephrol, 2018,19(1):240.

Mazzaferro S, Tartaglione L, Cascone C, et al. Multicenter study on parathyroidectomy (PTX) in Italy: preliminary results[J]. J Nephrol, 2018,31(5):767-773.

Portillo M R, Rodriguez-Ortiz M E. Secondary Hyperparthyroidism: Pathogenesis, Diagnosis, Preventive and Therapeutic Strategies[J]. Rev Endocr Metab Disord, 2017,18(1):79-95.

Lau W L, Obi Y, Kalantar-Zadeh K. Parathyroidectomy in the Management of Secondary Hyperparathyroidism[J]. Clin J Am Soc Nephrol, 2018,13(6):952-961.

Zhang Y, Lu Y, Feng S, et al. Evaluation of laboratory parameters and symptoms after parathyroidectomy in dialysis patients with secondary hyperparathyroidism[J]. Ren Fail, 2019,41(1):921-929.

Kestenbaum B, Andress D L, Schwartz S M, et al. Survival following parathyroidectomy among United States dialysis patients[J]. Kidney Int, 2004,66(5):2010-2016.

Bleyer A J, Burkart J, Piazza M, et al. Changes in cardiovascular calcification after parathyroidectomy in patients with ESRD[J]. Am J Kidney Dis, 2005,46(3):464-469.

Nishizawa Y, Shoji T, Kawagishi T, et al. Atherosclerosis in uremia: possible roles of hyperparathyroidism and intermediate density lipoprotein accumulation[J]. Kidney Int Suppl, 1997,62(62):S90-S92.

Bellasi A, Kooienga L, Block G A, et al. How long is the warranty period for nil or low coronary artery calcium in patients new to hemodialysis?[J]. J Nephrol, 2009,22(2):255-262.

McCullough P A, Jurkovitz C T, Pergola P E, et al. Independent components of chronic kidney disease as a cardiovascular risk state: results from the Kidney Early Evaluation Program (KEEP) [J]. Arch Intern Med, 2007,167(11):1122-1129.

Schiffrin E L, Lipman M L, Mann J F. Chronic kidney disease: effects on the cardiovascular system[J]. Circulation, 2007,116(1):85-97.

Ma Q, Su D, Liu F, et al. Parathyroidectomy Influences Coronary

Kestenbaum B, Seliger S L, Gillen D L, et al. Parathyroidectomy rates among United States dialysis patients: 1990-1999[J]. Kidney Int, 2004,65(1):282-288.

Dussol B, Morand P, Martinat C, et al. Influence of parathyroidectomy on mortality in hemodialysis patients: a prospective observational study[J]. Ren Fail, 2007,29(5):579-586.

Naranda J, Ekart R, Pecovnik-Balon B. Total parathyroidectomy with forearm autotransplantation as the treatment of choice for secondary hyperparathyroidism[J]. J Int Med Res, 2011,39(3): 978-987.

Gao Z, Li X, Miao J, et al. Impacts of parathyroidectomy on calcium and phosphorus metabolism disorder, arterial calcification and arterial stiffness in haemodialysis patients[J]. Asian J Surg, 2019,42(1):6-10.

Choi S R, Lee Y K, Cho A J, et al. Malnutrition, inflammation, progression of vascular calcification and survival: Inter-relationships in hemodialysis patients[J]. PLoS One, 2019,14(5):216415.

Neven E, De Schutter T M, De Broe M E, et al. Cell biological and physicochemical aspects of arterial calcification[J]. Kidney Int, 2011,79(11):1166-1177.

Jung S, Querfeld U, Muller D, et al. Submaximal suppression of parathyroid hormone ameliorates calcitriol-induced aortic calcification and remodeling and myocardial fibrosis in uremic rats[J]. J Hypertens, 2012,30(11):2182-2191.

Lioufas N, Toussaint N D, Pedagogos E, et al. Can we IMPROVE cardiovascular outcomes through phosphate lowering in CKD? Rationale and protocol for the IMpact of Phosphate Reduction On Vascular End-points in Chronic Kidney Disease (IMPROVE-CKD) study[J]. BMJ Open, 2019,9(2): 24382.

Kim H G, Song S W, Kim T Y, et al. Risk factors for progression of aortic arch calcification in patients on maintenance hemodialysis and peritoneal dialysis[J]. Hemodial Int, 2011,15(4):460-467.

Honkanen E, Kauppila L, Wikstrom B, et al. Abdominal aortic calcification in dialysis patients: results of the CORD study[J]. Nephrol Dial Transplant, 2008,23(12):4009-4015.

侯爱珍,肖观清,叶佩仪,等.甲状旁腺切除术后维持性血液透析 患者腹主动脉钙化的改变[J].中华肾脏病杂志,2020(3):183-184.

Chou F F, Chen J B, Huang S C, et al. Changes in serum FGF23 and Klotho levels and calcification scores of the abdominal aorta after parathyroidectomy for secondary hyperparathyroidism[J]. Am J Surg, 2019,218(3):609-612.

Jung S, Querfeld U, Muller D, et al. Submaximal suppression of parathyroid hormone ameliorates calcitriol-induced aortic calcification and remodeling and myocardial fibrosis in uremic rats[J]. J Hypertens, 2012,30(11):2182-2191.

师红红,张翠芳,吕程,等.甲状旁腺切除术后维持性血液透 析患者腹主动脉钙化

金其庄,王玉柱,叶朝阳,等.中国血液透析用血管通路专家共识 (第2版)[J].中国血液净化,2019,18(6):365-381.

曾海红,吴秀红,钱银玲,等.维持性血液透析患者动静脉内瘘失 功的原因分析

Tuysuz M E, Dedemoglu M. Calcium phosphate product level as a predictor for arteriovenous fistula re-operations in patients with chronic renal failure[J]. Vascular, 2019,27(3):284-290.

葛益飞,杨光,俞香宝,等.甲状旁腺全切除加前臂移植术后动 静脉内瘘早期失功的临床分析[J].中国血液净化,2019,18(6): 420-423.

Chen T Y, Lehman J S, Gibson L E, et al. Histopathology of Calciphylaxis: Cohort Study With Clinical Correlations[J]. Am J Dermatopathol, 2017,39(11):795-802.

Hassanein M, Laird-Fick H, Tikaria R, et al. Removing the problem: parathyroidectomy for calciphylaxis[J]. BMJ Case Rep, 2018,11(1).

McCarthy J T, El-Azhary R A, Patzelt M T, et al. Survival, Risk Factors, and Effect of Treatment in 101 Patients With Calciphylaxis[J]. Mayo Clin Proc, 2016,91(10):1384-1394.

Duffy A, Schurr M, Warner T, et al. Long-term outcomes in patients with calciphylaxis from hyperparathyroidism[J]. Ann Surg Oncol, 2006,13(1):96-102.




DOI: https://doi.org/10.12346/pmr.v4i3.6698

Refbacks

  • 当前没有refback。