Prx1的结构功能及其在相关疾病中的作用

俞辰 刘, 征 马, 晓璇 张, 亮 赵

摘要


过氧化物还原蛋白 1 属于过氧化物酶家族，广泛存在于生物中，对维持体内氧化 / 抗氧化系统的平衡发挥着重要作用，目前大量研究已表明 Prx1 与肿瘤、神经退行性疾病、糖尿病、缺血性脑卒中等存在明显相关性，为上述疾病的诊断、病情评估、治疗、预后等提供了理论依据，具有非常重要的临床意义。笔者主要就过氧化物还原蛋白 1 的结构功能以及其在相关疾病中的研究进展进行综述，旨在为进一步研究提供理论依据。

关键词


过氧化物还原蛋白 1；肿瘤；神经退行性疾病；动脉粥样硬化；缺血性脑卒中

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参考


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DOI: https://doi.org/10.12346/pmr.v4i3.6683

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