强直性脊柱炎患者MRI椎体角炎症和脂肪浸润与骨赘的相关性分析

晶 王, 献华 吴, 志峰 顾

摘要


目的：探讨强直性脊柱炎（Ankylosing spondylitis，AS）骨赘形成与椎体角炎症和（或）脂肪浸润之间的相关性。方法：纳入 AS 患者 82 例，记录年龄、病程、Bath 强直性脊柱炎活动度指数（BASDAI）、测量指数（BASMI）及功能指数（BASFI）；血沉，C- 反应蛋白；患者在入组时均行腰椎 X 线摄片及腰椎 MRI 扫描，分析患者骨赘、椎体角炎症及脂肪浸润有无。统计分析采用 SPSS24.0 软件。结果：椎体角炎症与疾病活动度明显相关，骨赘的形成与椎体角炎症 / 脂肪浸润有关，当炎症和脂肪浸润同时存在时，骨赘的发生率显著增高。结论：强直性脊柱炎椎体角炎症和局灶性脂肪浸润是参与骨赘形成的重要危险因素。

关键词


强直性脊柱炎；骨赘；椎角炎症；椎角脂肪浸润

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参考


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DOI: https://doi.org/10.12346/pmr.v3i5.4477

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