长链非编码 ＲＮＡ的功能特性及在肿瘤中的研究概述

梦思 张, 晋珩 徐, 晓娟 郑, 猛 赵

摘要


长链非编码 RNA(long non-coding RNA,Lnc RNA)可以预测出多种恶性肿瘤,并且可能会成为新的肿瘤标志和潜在治疗目标.这篇综述主要阐明了 Lnc RNA 的调节方式和功 能 性,讨 论 了Lnc RNA 作 为 一 种 诊 断、治 疗 和 预 期 的 作 用。后生物标志物潜在的临床用途,并简略概述Lnc RNA 在各种系统肿瘤中的表现和研究情况,尤其是结直肠癌。

关键词


长链非编码RNA;调控机制;恶性肿瘤

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参考


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DOI: https://doi.org/10.36012/pmr.v2i4.2737

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