Discussion on the Medication Rule of Children’s Cough in Ancient Medical books Based on Data Mining

Abstract

Objective: To explore the medication rule of children’s cough in ancient medical books by using the tradi- tional Chinese Medicine Inheritance calculation platform. Methods: By collecting the prescriptions for the treatment of children’s cough in the Great Dictionary of traditional Chinese medicine prescriptions, the prescription information was entered into the traditional Chinese Medicine Inheritance calculation platform (V3.0), the frequency, four properties, five flavors and meridian tropism of the entered prescriptions were counted, and the common drug pairs, core combina- tions and new prescription combinations were obtained by using the methods of association principles and cluster anal- ysis. Results: A total of 106 prescriptions and 203 traditional Chinese medicines were selected, and the cumulative use frequency was 1061 times. Among them, there are 12 traditional Chinese medicines used more than 20 times, and the top three are Platycodon grandiflorum, Bitter almond and Pinellia ternary. The top three traditional Chinese medicine efficacy categories are expectorant drugs, antitussive and antiasthmatic drugs, antipyretic drugs and drugs for relieving exterior syndrome. The four properties are mainly warm and cold, the five flavors are mainly spicy, bitter and sweet. It’s Channel tropism mostly goes to lung, spleen and stomach meridians. Five common couplet medicines, twenty-three core combinations of traditional Chinese medicine and three new traditional Chinese medicine prescription were ob- tained. Conclusions: Ancient doctors used cold and warm drugs to treat children’s cough. Most of the drugs are pun- gent, bitter and sweet. Drugs mainly belong to lung meridian, followed by spleen meridian and stomach meridian, the main treatment methods are to expel wind and clear heat, eliminate dampness and dissipate phlegm, dispersing lung and relieve asthma, and appropriately add drugs for reducing Qi and moistening intestines.